BUA Institution

Charité - Universitätsmedizin Berlin

Description of research

My research focuses on the “sweet talk” between microbes and the airways: how sugar structures on airway epithelial surfaces influence host-pathogen interactions. In my doctoral thesis, I investigate how α-(1,2)-fucosylation and FUT2 secretor genotype shape pneumococcal pneumonia, a major form of community-acquired pneumonia.

Where in the world has your career been largely based until now?

Mostly Berlin so far. Scientifically, I keep oscillating between translational medical research, infection biology and glycobiology.

Why Berlin?

The molecular dialogue between microbes and airway surfaces rarely respects disciplinary boundaries - and Berlin offers an ideal environment for interdisciplinary research. Through the BUA X-Tutorials and Collaborative Research Centre 1449 “Dynamic Hydrogels at Biointerfaces”, I have access to excellent structures that enable and encourage collaboration across fields.

What fascinates you about your research area?

What fascinates me is that the airways are not protected by a simple wall, but by dynamic biological interfaces - mucus, glycocalyx and epithelial surface structures. The way these interfaces communicate with microbes may determine whether they are kept at a distance or whether they attach and invade.

What major short-term goal are you currently working towards with your research?

Together with Helge Baumann, I co-lead a BUA-funded X-Tutorial on how airway sugars shape Pseudomonas aeruginosa infection. In collaboration with enthusiastic BUA students, we aim to channel our shared scientific curiosity into interdisciplinary research and meaningful scientific output.

How did you become interested in your specific topic?

It really started with meeting my current mentors. Their enthusiasm for the field was contagious, and what began as curiosity grew through my doctoral project into a research path I am very happy to keep following.

What would be the greatest professional achievement you could ever aspire to?

To contribute to research that genuinely changes how we understand or treat respiratory infections.