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How sugars in the airways drive Pseudomonas aeruginosa infection.

Sebastian Schickinger, Helge Baumann, Charité - Universitätsmedizin Berlin, Hochschule, Fächerverbund Infektiologie, Pneumologie und Intensivmedizin

Inhalte/ Contents

Chronic airway infections are a major cause of morbidity and mortality in diseases such as cystic fibrosis and COPD. One key driver is the bacterium Pseudomonas aeruginosa. Evidence suggests that certain sugars in the airways promote microbial growth and infection dynamics, but the role of many non-glucose monosaccharides remains unclear. In this X Tutorial, we invite you to explore how non-glucose sugars in the airways affect Pseudomonas aeruginosa infections. You can choose from work packages ranging from a few weeks to extended projects. Together, we will quantify sugars in patient derived samples, test their effects on bacterial growth and 2D infection models, and examine their impact in advanced air liquid interface systems. You will play an active role in translational respiratory research alongside peers from medicine, biology, biotechnology, biochemistry and related life sciences, unlocking the collaborative research potential of the Berlin University Alliance.

Kontakt/ Contact

sebastian.schickinger@charite.de

Link zum Vorlesungsverzeichnis/ Link to the course catalogue

folgt/ coming